DIFFERENT IPSC-DERIVED NEURAL STEM CELLS SHOWS VARIOUS SPECTRUMS OF SPONTANEOUS DIFFERENTIATION DURING LONG TERM CULTIVATION

Different iPSC-derived neural stem cells shows various spectrums of spontaneous differentiation during long term cultivation

IntroductionCulturing of human neural stem cells (NSCs) derived from induced pluripotent stem cells (iPSC) is a promising area of research, KEY MODULE as these cells have the potential to treat a wide range of neurological, neurodegenerative and psychiatric diseases.However, the development of optimal protocols for the production and long-term cult

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Delving into the significance of the His289Tyr single-nucleotide polymorphism in the glutamate ionotropic receptor kainate-1 (Grik1) gene of a genetically audiogenic seizure model

Genetic abnormalities affecting glutamate receptors are central to excitatory overload-driven neuronal mechanisms that culminate in seizures, making them pivotal targets in epilepsy research.Increasingly used to advance this field, the genetically audiogenic seizure hamster from Salamanca (GASH/Sal) exhibits generalized seizures triggered by high-i

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Quel avenir pour la gestion des parties prenantes?

The concept of stakeholders is, without any doubt, one of the most important contributions to the field of business ethics in the recent years.This concept articulates a moral requirement in virtue of which managers must consider the interests of all stakeholders.In its most common form, the list of stakeholders includes the employees, the Vitamins

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